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AST-1306 Tosilate

Catalog No.: R10006
CAS No.: 1050500-29-2
Formula: C24H18N4O2FCl.C9H12Os
Weight: 617.1327
Details:
Theoretical analysis

CAS NO.:1050500-29-2

Molecular Formula:C24H18N4O2FCl.C9H12Os

Molecular Weight:617.1327

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases.
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

Product will be shipped with supporting analytical data.

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