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Cat.No. Product name Product Description
R10007 AZD6244 Selumetinib (AZD6244) is a potent, highly selective MEK1 inhibitor with IC50 of
R10031 BIIB-024; MLN2480 MLN2480(BIIB-024) is an oral, selective pan-Raf kinase inhibitor in chinical tri
R10068 GSK1120212; Trametinib; JTP74057 Trametinib (GSK1120212) is a highly specific and potent MEK1/2 inhibitor with IC
R10074 AZ628 AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 1
R10190 BIX02188 BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK
R10216 PLX4032 Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with
R10250 TAK632 TAK-632 is a potent pan-Raf inhibitor with IC50 of 8.3 nM and 1.4 nM for B-Raf(w
R10412 Vemurafenib (PLX4032, RG7204) Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with
R10680 ZM336372 ZM 336372 is a potent and selective c-Raf inhibitor with IC50 of 70 nM, 10-fold
R10829 SCH772984 SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM in
R10934 BI-847325 BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibi
R10942 Binimetinib; MEK162,ARRY-162,ARRY-438162 Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with
R10952 Cobimetinib;GDC-0973; XL518 Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor w
R11503 Dabrafenib (GSK2118436) Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8
R11507 BMS-582949;BMS582949 BMS-582949 is a potent and selective p38 mitogen-activated protein kinase (p38 M
R11583 Ravoxertinib (GDC-0994) GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50
R11586 DEL-22379;DEL22379 DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ∼0.5 μM.
R2032487 PD318088 PD318088 is an allosteric MEK inhibitor.
R2032746 GDC-0879 GDC-0879 is a potent and selective B-Raf inhibitor with an IC50 of 0.13 nM.
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