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Home > Products > Protein Tyrosine Kinase
Cat.No. Product name Product Description
R10003 BGJ398; NVP-BGJ398 BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with
R10006 AST-1306 Tosilate AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM
R10036 XL880; Foretinib; GSK136308 Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly
R10037 ANA12 ANA-12 is a selective TrkB antagonist with Kd of 10 nM and 12 μM for the high an
R10042 CO1686; Rociletinib Rociletinib (CO-1686, AVL-301) is an irreversible, mutant-selective EGFR inhibit
R10052 GNF-5837 GNF-5837 is a selective, and orally bioavailable pan-TRK inhibitor for TrkA, and
R10054 TAE684 TAE684 (NVP-TAE684) is a potent and selective ALK inhibitor with IC50 of 3 nM in
R10058 Masitinib Masitinib is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540
R10061 Nexavar; Bay 43-9006; Sorafenib Sorafenib Tosylate is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with I
R10062 SAR131675 SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays,
R10064 Brivanib; BMS540215 Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, mode
R10076 Crizotinib; PF02341066 Crizotinib (PF-02341066) is a potent inhibitor of c-Met and ALK with IC50 of 11
R10077 AMG208 AMG 208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
R10078 EMD1214063 Tepotinib (EMD 1214063) is a potent and selective c-Met inhibitor with IC50 of 4
R10087 AZD9291 Osimertinib (AZD9291) is an oral, irreversible, and mutant-selective EGFR inhibi
R10103 Cedirannib; AZD2171 Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of 1000-fo
R10114 PHA665752 PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50
R10115 SU11274 U11274 is a selective Met inhibitor with IC50 of 10 nM in cell-free assays, no e
R10116 OSI906 OSI-906 (Linsitinib) is a selective inhibitor of IGF-1R with IC50 of 35 nM in ce
R10118 Regorafenib; BAY73-4506; BAY734506 Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3
R10126 WZ4002 WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with
R10127 ABT869 Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for
R10134 BMS599626 Free base AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 wit
R10138 AV-951; Tivozanib Tivozanib (AV-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with
R10143 BMS907351; XL184; Cabozantinib Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035
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