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Cabozantinib (XL184; BMS-907351)

Catalog No.: R10143
CAS No.: 849217-68-1
Formula: C₂₈H₂₄FN₃O₅
Weight: 501.51
Details:
Theoretical analysis

CAS NO.:849217-68-1

Molecular Formula:C₂₈H₂₄FN₃O₅

Molecular Weight:501.51

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively.
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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