R10031 |
BIIB-024; MLN2480 |
MLN2480(BIIB-024) is an oral, selective pan-Raf kinase inhibitor in chinical tri
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R10074 |
AZ628 |
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 1
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R10216 |
PLX4032 |
Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with
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R10250 |
TAK632 |
TAK-632 is a potent pan-Raf inhibitor with IC50 of 8.3 nM and 1.4 nM for B-Raf(w
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R10412 |
Vemurafenib (PLX4032, RG7204) |
Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with
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R10680 |
ZM336372 |
ZM 336372 is a potent and selective c-Raf inhibitor with IC50 of 70 nM, 10-fold
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R11503 |
Dabrafenib (GSK2118436) |
Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8
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R2032746 |
GDC-0879 |
GDC-0879 is a potent and selective B-Raf inhibitor with an IC50 of 0.13 nM.
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