R10001 |
R788; Fostamatinib |
Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor
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R10002 |
R406 Free base |
R406 (free base) is a potent Syk inhibitor with IC50 of 41 nM in a cell-free ass
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R10003 |
Infigratinib (Synonyms: BGJ-398; NVP-BGJ398) |
BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with
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R10004 |
VX-809; Lumacaftor |
VX-809 (Lumacaftor) acts to correct CFTR mutations common in cystic fibrosis by
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R10005 |
AT406 (SM-406, ARRY-334543) |
AT-406 is an orally bioavailable inhibitor of IAP family of proteins with potent
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R10006 |
Allitinib tosylate (Synonyms: AST-1306 (TsOH))/897383-62-9 Free base |
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM
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R10007 |
AZD6244 |
Selumetinib (AZD6244) is a potent, highly selective MEK1 inhibitor with IC50 of
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R10008 |
Rucaparib phosphate; AG014699; PF01367388 |
Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for
|
R10009 |
AZD8055 |
AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM in MDA-MB-
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R10010 |
Rucaparib; AG-014699; PF-01367388 |
Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for
|
R10011 |
BIO-acetoxime; GSK3 Inhibitor IX |
BIO-acetoxime is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fol
|
R10012 |
NVP-HSP990 (HSP990) |
NVP-HSP990 (HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90α/
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R10013 |
PF 04691502 |
PF-04691502 is an ATP-competitive PI3K(α/β/δ/γ)/mTOR dual inhibitor with Ki of 1
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R10014 |
AKT inhibitor VIII (AKTI-1/2) |
CAS NO.:612847-09-3Product Name:1-(1-(4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-
|
R10015 |
MN-64 |
MN-64 is a inhibitor of tankyrases, showed 6 nM potency against tankyrase 1, iso
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R10016 |
TH287 |
TH287 is a potent and selective MTH1 (NUDT1) inhibitor with IC50 of 0.8 nM.
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R10019 |
Setanaxib (Synonyms: GKT137831; GKT831) |
Setanaxib (GKT137831) is a selective NADPH oxidase (NOX1/4) inhibitor with Kis o
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R10020 |
JNJ-31020028 |
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 recept
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R10022 |
GSK429286A |
GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63
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R10024 |
Cardiogenol C hydrochloride |
Cardiogenol C hydrochloride is a cell-permeable pyrimidine compound which potent
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R10025 |
MLN2238 |
MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteaso
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R10026 |
Ruxolitinib (INCB018424) |
CAS NO.:941678-49-5Product Name:β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl
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R10027 |
KU-0063794 |
KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTO
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R10028 |
MLN9708 |
MLN9708 immediately hydrolyzed to MLN2238, the biologically active form, on expo
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R10029 |
ML141 (CID-2950007) |
ML141 is a potent, selective and reversible non-competitive inhibitor of Rho fam
|