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Home > Products > Apoptosis
Cat.No. Product name Product Description
R10005 AT406 (SM-406, ARRY-334543) AT-406 is an orally bioavailable inhibitor of IAP family of proteins with potent
R10039 Venetoclax; ABT-199; GDC-0199 Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of 4800-fo
R10043 ABT-263; Navitoclax ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of
R10094 NSC 652287 RITA (NSC 652287) induces both DNA-protein and DNA-DNA cross-links with no detec
R10095 Tenovin1 Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquit
R10119 PAC1 PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first smal
R10257 VX765; Belnacasan Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of
R10333 ABT263;Navitoclax ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of
R10350 UMI-77 UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity ove
R10362 GSK2606414 GSK2606414 is an orally available, potent, and selective PERK inhibitor.
R10370 GSK2656157 GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC(50
R10425 Spautin1 Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells
R10511 Lenalidomide; CC5013 Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMC
R10553 Venetoclax; ABT199 Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of 4800-fo
R10603 JNJ26854165 JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also in
R10628 Apoptosis Activator2 Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and
R10655 Necrostatin-1 Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosi
R10763 Kevetrin hydrochloride; NSC525990 Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor
R10786 FMK FMK is a RSK2 kinase inhibitor.
R10798 LCL161 LCL161 is an orally bioavailable second mitochondrial-derived activator of caspa
R10799 LCL161 Enantiomer LCL161 is an orally bioavailable second mitochondrial-derived activator of caspa
R10802 Nutlin-3 MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.
R10827 RG7112 RG7112 is the first clinical small-molecule MDM2 inhibitor designed to occupy th
R11535 NSC59984 NSC59984 is a p53 pathway activator via induction of mutant p53 protein degradat
R11566 Tasisulam Tasisulam is an antitumor agent and an apoptosis inducer via the intrinsic pathw
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