R10022 |
GSK429286A |
GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63
|
R10029 |
ML141 (CID-2950007) |
ML141 is a potent, selective and reversible non-competitive inhibitor of Rho fam
|
R10083 |
XL413 Hydrochloride |
XL413 (BMS-863233) is a potent and selective cell division cycle 7 homolog (CDC7
|
R10090 |
AZD5438 |
AZD5438 is a potent inhibitor of CDK1/2/9 with IC50 of 16 nM/6 nM/20 nM in cell-
|
R10139 |
Roscovitine; Seliciclib |
Roscovitine (Seliciclib, CYC202) is a potent and selective CDK inhibitor for Cdc
|
R10189 |
AT7519 HCl |
AT7519 HCl is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210
|
R10219 |
AZD7762;AZD-7762 |
AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM in a cell-
|
R10252 |
MK1775 |
MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-f
|
R10264 |
RO3280 |
RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with
|
R10271 |
BI 2536;BI2536 |
BI 2536 is a dual PLK1 and BRD4 inhibitor with IC50s of 0.83 and 25 nM, respecti
|
R10314 |
PD0332991; PD0332991; Palbociclib |
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 wi
|
R10341 |
BS-181 hydrochloride |
BS-181 HCl is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more t
|
R10377 |
Palbociclib hydrochloride;PD 0332991 hydrochloride |
Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50
|
R10417 |
EHop016 |
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-
|
R10616 |
ZCL278 |
ZCL278 is a selective Cdc42 GTPase inhibitor with Kd of 11.4 μM.
|
R10701 |
CCG1423 |
CCG-1423 is a specific RhoA pathway inhibitor, which inhibits SRF-mediated trans
|
R10707 |
PURVALANOLA |
Purvalanol A is a potent, and cell-permeable CDK inhibitor with IC50 of 4 nM, 70
|
R10729 |
BML-277 |
BML-277 (Chk2 Inhibitor II) is a Chk2 (checkpoint kinase 2) inhibitor.
|
R10755 |
BPR1J-097 |
BPR1J-097 is a novel small molecule FLT-3 inhibitor(IC50=11±7 nM) with promising
|
R10910 |
MK-8776 |
MK-8776 (SCH 900776) is a selective Chk1 inhibitor with IC50 of 3 nM in a cell-f
|
R11042 |
HMN214 |
HMN-214 is a prodrug of HMN-176, which alters the cellular spatial orientation o
|
R11449 |
AT7519 |
AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM.
|
R11461 |
Abemaciclib methanesulfonate (LY2835219 methanesulfonate) |
LY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM
|
R11591 |
GSK-461364; GSK-461364A |
GSK461364 inhibits purified Plk1 with Ki of 2.2 nM in a cell-free assay. It is m
|
R11611 |
KENPAULLONE |
Kenpaullone is an ATP-competitive inhibitor of cyclin-dependent kinases (CD
|