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  • sugammadex sodium;org 25969

    sugammadex sodium;org 25969

    R11425
    Sugammadex (Org 25969, tradename Bridion) is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA).
  • WIN35428

    WIN35428

    R11395
    (–)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane (β-CFT, WIN 35,428) is a stimulant drug used in scientific research. CFT is a phenyltropane based dopamine reuptake inhibitor and is structurally deriv
  • Deoxynivalenol

    Deoxynivalenol

    R11198
    Vomitoxin, also known as deoxynivalenol (DON), is a type B trichothecene, an epoxy-sesquiterpenoid. This mycotoxin occurs predominantly in grains such as wheat, barley, oats, rye, and maize, and less
  • Eliglustat (Tartrate)

    Eliglustat (Tartrate)

    R11057
    Eliglustat tartrate (Genz-112638), a specific inhibitor of glucosylceramide synthase, is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1).
  • Anamorelin ; RC-1291

    Anamorelin ; RC-1291

    R11015
    Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia.
  • Eliglustat

    Eliglustat

    R11006
    Eliglustat (Tartrate) inhibits glucosylceramide synthase(GCS),thus reducing the load of glucosylceramide influx into the lysosome.
  • Tenofovir Alafenamide (GS-7340)

    Tenofovir Alafenamide (GS-7340)

    R10583
    CAS NO.:379270-37-8Product Name:(S)-Isopropyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoateSynonyms:EINEC:Molecular Formula:C21H29N6O5PMolecular W
  • AKT inhibitor VIII (AKTI-1/2)

    AKT inhibitor VIII (AKTI-1/2)

    R10014
    CAS NO.:612847-09-3Product Name:1-(1-(4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-oneSynonyms:EINEC:Molecular Formula:C34H29N7OMolecular Weight:551.64
  • PF04691502

    PF04691502

    R10013
    PF-04691502 is an ATP-competitive PI3K(α/β/δ/γ)/mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK,
  • AST-1306 Tosilate

    AST-1306 Tosilate

    R10006
    AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective f
  • AT406 (SM-406, ARRY-334543)

    AT406 (SM-406, ARRY-334543)

    R10005
    AT-406 is an orally bioavailable inhibitor of IAP family of proteins with potential apoptotic inducing and antineoplastic activity. AT-406 selectively inhibits the biological activity of IAP proteins,
  • VX-809; Lumacaftor

    VX-809; Lumacaftor

    R10004
    VX-809 (Lumacaftor) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation,EC50 of 0.1 μM in fisher rat thyroid cells. Phase 3.
  • R788; Fostamatinib

    R788; Fostamatinib

    R10001
    Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.
  • BGJ398; NVP-BGJ398

    BGJ398; NVP-BGJ398

    R10003
    BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM in cell-free assays, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity