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Avitinib (AC0010)

Catalog No.: R10996
CAS No.: 1557267-42-1
Formula: C26H26FN7O2
Weight: 487.53
Details:
Theoretical analysis

CAS NO.:1557267-42-1

Molecular Formula:C26H26FN7O2

Molecular Weight:487.53

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
Avitinib (AC0010) is a pyrrolopyrimidine-based irreversible EGFR inhibitor that is mutation-selective with IC50 value of 0.18 nM against EGFR L858R/T790M double mutations, nearly 43-fold greater potency over wild-type EGFR (IC50 value, 7.68 nM). It has comparable anti-tumor activity and tolerated toxicity.
Availability and price

Packing: 10mg/50mg/100mg/500mg/1g and we provide a variety of packaging.

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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

Product will be shipped with supporting analytical data.

Fast delivery about 4-5 working days.

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