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Tivozanib;AV-951; KRN951

Catalog No.: R10138
CAS No.: 475108-18-0
Formula: C22H19N4O5Cl
Weight: 454.86306
Details:
Theoretical analysis

CAS NO.:475108-18-0

Molecular Formula:C22H19N4O5Cl

Molecular Weight:454.86306

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
Tivozanib (AV-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

Product will be shipped with supporting analytical data.

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