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AP24534; Ponatinib

Catalog No.: R10181
CAS No.: 943319-70-8
Formula: C29H27F3N6O
Weight: 532.559496164322
Details:
Theoretical analysis

CAS NO.:943319-70-8

Molecular Formula:C29H27F3N6O

Molecular Weight:532.559496164322

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively.
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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