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Semagacestat (LY450139)
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Details:
Theoretical analysis
CAS NO.:425386-60-3
Molecular Formula:C19H27N3O4
Molecular Weight:361.43538
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM in H4 human glioma cell. Phase 3.
Availability and price
Packing: 10mg/50mg/100mg/500mg/1g and we provide a variety of packaging.
We offer significant discount for larger quantity order.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Product will be shipped with supporting analytical data.
Fast delivery about 4-5 working days.
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