CAL101 Intermediate1

CAS NO.:870281-85-9

Molecular Formula:C₂₂H₂₄N₃O₃F

Molecular Weight:397.44266

CAL-101 (Idelalisib, GS-1101) is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.

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