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CO1686 Intermediate2
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Details:
Theoretical analysis
CAS NO.:1374507-23-9
Molecular Formula:C16H16ClF3N4O2
Molecular Weight:388.77
Description
Rociletinib (CO-1686, AVL-301) is an irreversible, mutant-selective EGFR inhibitor with Ki of 21.5 nM and 303.3 nM for EGFRL858R/T790M and EGFRWT in cell-free assays, respectively. Phase 2.
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