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(E)-SIS3

Catalog No.: R11392
CAS No.: 521984-48-5
Formula: C28H27N3O3.HCl
Weight: 489.99322
Details:
Theoretical analysis

CAS NO.:521984-48-5

Molecular Formula:C28H27N3O3.HCl

Molecular Weight:489.99322

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
(E)-SIS3 is a specific, cell-permeable, and selective Smad3 inhibitor, which inhibits Smad3 phosphorylation with an IC50 of 3 µM. (E)-SIS3 also inhibits the myofibroblast differentiation of fibroblasts by TGF-β1.
Availability and price

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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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