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Dolutegravir sodium (Synonyms: S/GSK1349572 sodium)
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Details:
Theoretical analysis
CAS NO.:1051375-19-9
Molecular Formula:C₂₀H₁₈F₂N₃NaO₅
Molecular Weight:441.36062
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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