Solithromycin (Synonyms: CEM-101; OP-1068)

CAS NO.:760981-83-7

Molecular Formula:C₄₃H₆₅FN₆O₁₀

Molecular Weight:845.008815526962

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Solithromycin (CEM-101) is an orally bioavailable, particularly effective antimicrobial agent, with IC₅₀s for Solithromycin inhibition of cell viability, protein synthesis, and growth rate are 7.5 ng/mL, 40 ng/mL, and 125 ng/mL for Streptococcus pneumonia, Staphylococcus aureus, and Haemophilus influenzae, respectively. Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis.

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