ML216 (Synonyms: CID-49852229)

CAS NO.:1430213-30-1

Molecular Formula:C₁₅H₉N₅OF₄S

Molecular Weight:383.32346

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

ML216(CID-49852229) is a potent inhibitor of the DNA unwinding activity of BLM helicase; showing similar IC50s of 3.0 and 0.97 μM for full length BLM and BLM636–1298 respectively. IC50 value: 3.0/0.97 uM(Full length/636–1298 BLM) Target: BLM helicase inhibitor ML216 shows cell-based activity, and can induce sister chromatid exchanges, enhance to the toxicity of aphidicolin and exert anti-proliferative activity in cells expressing BLM, but not in those lacking BLM. 

Packing: 10mg/50mg/100mg/500mg/1g and we provide a variety of packaging.

We offer significant discount for larger quantity order.

For quotation, question, and order, please send email to sales@rechemscience.com

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

Product will be shipped with supporting analytical data.

Fast delivery about 4-5 working days.