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IOX4
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Details:
Theoretical analysis
CAS NO.:1154097-71-8
Molecular Formula:C₁₅H₁₆N₆O₃
Molecular Weight:328.33
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
IOX4 is a selective HIF prolyl-hydroxylase 2 (PHD2) inhibitor with an IC50 value of 1.6 nM, induces HIFα in cells and in wildtype mice with marked induction in the brain tissue. IOX4 competes with and displaces 2-oxoglutarate (2OG) at the active site of PHD2.
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Quality control data
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