Prexasertib dihydrochloride (Synonyms: LY2606368 (dihydrochloride))

CAS NO.:1234015-54-3

Molecular Formula:C₁₈H₂₀ClN₇O₂

Molecular Weight:401.850101470947

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Prexasertib dihydrochloride (LY2606368 dihydrochloride) is a potent and selective ATP competitive inhibitor of the Chk1 protein kinase, with IC50s of <1 nM and 8 nM for CHK1 and CHK2, respectively, and a Ki of 0.9 nM against purified CHK1. 

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