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Compound E;Compound E (secretase inhibitor)；DuPont E)
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Details:
Theoretical analysis
CAS NO.:209986-17-4
Molecular Formula:C18H21NO3.C10H14O4.H3O4P
Molecular Weight:595.57522
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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