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Entrectinib (NMS-E628; RXDX-101)

Catalog No.: R181214
CAS No.: 1108743-60-7
Formula: C31H34F2N6O2
Weight: 560.637473583221
Details:
Theoretical analysis

CAS NO.:1108743-60-7

Molecular Formula:C31H34F2N6O2

Molecular Weight:560.637473583221

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
Entrectinib (NMS-E628) is a potent, orally available, and CNS-active pan-Trk, ROS1, and ALK inhibitor. Entrectinib inhibits TrkA, TrkB, TrkC, ROS1 and ALK with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Antitumor activity. 
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

Product will be shipped with supporting analytical data.

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