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QNZ46

Catalog No.: R910244
CAS No.: 237744-13-6
Formula: C24H17N3O6
Weight: 443.41
Details:
Theoretical analysis

CAS NO.:237744-13-6

Molecular Formula:C24H17N3O6

Molecular Weight:443.41

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
QNZ46 is a NMDA receptor antagonist. QNZ46 inhibits NMDA receptor function in a noncompetitive and voltage-independent manner by an unconventional mechanism that requires binding of glutamate to the GluN2 subunit, but not glycine binding to the GluN1 subunit. QNZ46 could provide an opportunity for the development of pharmacological tools and therapeutic agents that target NMDA receptors at a new site and modulate function by a novel mechanism. NMDA receptors are ionotropic glutamate receptors that mediate excitatory synaptic transmission and have been implicated in several neurological diseases.
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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