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PZ-2891

Catalog No.: R910290
CAS No.: 2170608-82-7
Formula: C₂₀H₂₃N₅O
Weight: 349.43
Details:
Theoretical analysis

CAS NO.:2170608-82-7

Molecular Formula:C₂₀H₂₃N₅O

Molecular Weight:349.43

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively. 
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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