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PZ-2891
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Details:
Theoretical analysis
CAS NO.:2170608-82-7
Molecular Formula:C₂₀H₂₃N₅O
Molecular Weight:349.43
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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