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Pralsetinib (Synonyms: BLU-667)
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Details:
Theoretical analysis
CAS NO.:2097132-94-8
Molecular Formula:C₂₇H₃₂FN₉O₂
Molecular Weight:533.60
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC50s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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