Tyrphostin AG 528 (Synonyms: Tyrphostin B66; AG 528)

CAS NO.:133550-49-9

Molecular Formula:C₁₈H₁₄N₂O₃

Molecular Weight:306.32

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Tyrphostin AG 528 is an inhibitor of EGFR and ErbB2 with IC50s of 4.9 and 2.1 μM, respectively. Tyrphostin AG 528 (Tyrphostin B66) is a protein tyrosine kinase inhibitor, with IC50s of 4.9 μM for epidermal growth factor receptors (EGFR) and 2.1 μM for ErbB2. Tyrphostin AG 528 is also an anticancer agent. 

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