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BH3I-1 (BHI1; BH 3I1)
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Details:
Theoretical analysis
CAS NO.:300817-68-9
Molecular Formula:C15H14BrNO3S2
Molecular Weight:400.310560703278
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4±0.2 μM in FP assay. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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