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Gedatolisib;PKI-587;PF-05212384
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Details:
Theoretical analysis
CAS NO.:1197160-78-3
Molecular Formula:C₃₂H₄₁N₉O₄
Molecular Weight:615.73
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ, and mTOR with IC50s of 0.4 nM, 5.4 nM and 1.6 nM, respectively.PKI-587 is equally effective in both complexes of mTOR, mTORC1 and mTORC2.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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