S1RA(E-52862)

CAS NO.:878141-96-9

Molecular Formula:C₂₀H₂₃N₃O₂

Molecular Weight:337.42

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM) antagonist, showed good selectivity against σ2R (Ki > 1000 nM).IC50 value: 17 nM (Ki) Target: σ1R in vitro: S1RA behaved as a highly selective σ1 receptor antagonist.

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