ADX-47273

CAS NO.:851881-60-2

Molecular Formula:C₂₀H₁₇F₂N₃O₂

Molecular Weight:369.36

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

ADX-47273 is a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).IC50 value: 170 nM(EC50) Target: positive allosteric modulator (PAM) of mGluR5 in vitro: ADX-47273 increased (9-fold) the response

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