NPS2143;NPS-2143(SB-262470A)

CAS NO.:284035-33-2

Molecular Formula:C₂₄H₂₅ClN₂O₂

Molecular Weight:408.92

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist.NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ recep

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