MK-886 (L 663536)

CAS NO.:118414-82-7

Molecular Formula:C₂₇H₃₄ClNO₂S

Molecular Weight:472.08

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively).MK-886 is also a non-competitive PPARα antagonist and can

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