LY3214996

CAS NO.:1951483-29-6

Molecular Formula:C₂₂H₂₇N₇O₂S

Molecular Weight:453.56

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

LY3214996 is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays.LY3214996 potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines.LY3214996 shows potent antitumor activities in cancer

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