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Dactolisib;BEZ235;NVP-BEZ235
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Details:
Theoretical analysis
CAS NO.:915019-65-7
Molecular Formula:C₃₀H₂₃N₅O
Molecular Weight:469.54
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Dactolisib (BEZ235) is a dual pan-class I PI3K and mTOR kinase inhibitor with IC50s of 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR, respectively.Dactolisib (BEZ235) inhibits both mTORC1 and mTORC2.
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Quality control data
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