BMS777607;BMS-777607;BMS 817378

CAS NO.:1025720-94-8

Molecular Formula:C₂₅H₁₉ClF₂N₄O₄

Molecular Weight:512.89

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

BMS 777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivit

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