Telaglenastat(CB-839)

CAS NO.:1439399-58-2

Molecular Formula:C₂₆H₂₄F₃N₇O₃S

Molecular Weight:571.57

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Telaglenastat (CB-839) is a first-in-class, reversible and orally bioavailable glutaminase 1 (GLS1) inhibitor.Telaglenastat (CB-839) selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2.The IC50s

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