Necrostatin-1

CAS NO.:4311-88-0

Molecular Formula:C₁₃H₁₃N₃Os

Molecular Weight:259.33

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Necrostatin-1 (Nec-1) is a potent, selective and cell-permeable necroptosis inhibitor with an EC50 of 490 nM in Jurkat cells.Necrostatin-1 acts by inhibiting RIP1 kinase (EC50=182 nM) in the necroptosis pathway.Necrostatin-1 is also a indoleamine-2,3-diox

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