SGC0946

CAS NO.:1561178-17-3

Molecular Formula:C₂₈H₄₀BrN₇O₄

Molecular Weight:618.57

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

SGC0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM; selectively kill mixed lineage leukaemia cells.IC50 value: 0.3 nM(DOT1L) Target: selective DOT1L inhibitor SGC 0946 is over 100-fold selective for other histon

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