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SNX-2112(PF-04928473)

Catalog No.: R2032762
CAS No.: 908112-43-6
Formula: C₂₃H₂₇F₃N₄O₃
Weight: 464.48
Details:
Theoretical analysis

CAS NO.:908112-43-6

Molecular Formula:C₂₃H₂₇F₃N₄O₃

Molecular Weight:464.48

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
SNX-2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM for Hsp90 and IC50s of 30 nM, 30 nM for Hsp90 α and Hsp90 β, also induces Her-2 degradation, and inhibits Grp94 and Trap-1, with IC50s of 10 nM, 4.275 μM and 0.862 μM, respecti
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Quality control data

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