AS1842856

CAS NO.:836620-48-5

Molecular Formula:C₁₈H₂₂FN₃O₃

Molecular Weight:347.38

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

AS1842856, a specific Foxo1 inhibitor (IC50=30 nM), potently suppresses autophagy.AS1842856 inhibits FoxO1 activity by suppressing the expression of SIRT1.AS1842856 only reduces the activity of FoxO1 by binding with it, without affecting its transcription

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