GNE-490

CAS NO.:1033739-92-2

Molecular Formula:C₁₈H₂₂N₆O₂S

Molecular Weight:386.47

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

GNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR.It has good pharmacokinetic (PK) parameters and demonstrates knock down of pathway markers in vivo.Originally obtained via modification of compounds like GDC-0941, GN

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