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TAK779
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Details:
Theoretical analysis
CAS NO.:229005-80-5
Molecular Formula:C₃₃H₃₉ClN₂O₂
Molecular Weight:531.13
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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