Edicotinib(JNJ-40346527;JNJ-527)

CAS NO.:1142363-52-7

Molecular Formula:C₂₇H₃₅N₅O₂

Molecular Weight:461.6

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Edicotinib (JNJ-40346527; JNJ-527) is a potent, selective, brain penetrant and orally active colony-stimulating factor-1 receptor (CSF-1R) inhibitor with an IC50 of 3.2 nM.Edicotinib exhibits less inhibitory effects on KIT and FLT3 with IC50 values of 20

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