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ML221
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Details:
Theoretical analysis
CAS NO.:877636-42-5
Molecular Formula:C₁₇H₁₁N₃O₆S
Molecular Weight:385.35
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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