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PF-5274857
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Details:
Theoretical analysis
CAS NO.:1373615-35-0
Molecular Formula:C₂₀H₂₅ClN₄O₃S
Molecular Weight:436.96
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood–brain barrier.
Availability and price
Packing: 10mg/50mg/100mg/500mg/1g and we provide a variety of packaging.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Product will be shipped with supporting analytical data.
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