PTC028

CAS NO.:1782970-28-8

Molecular Formula:C₁₉H₁₂F₅N₅

Molecular Weight:405.32

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer.PTC-028 selectively inhibits cancer cells whereas normal cells remain unaffected.Depletion of BMI-1 by PTC-028 induces caspase-mediated apoptosis.

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