BL-918(compound 33i)

CAS NO.:2101517-69-3

Molecular Formula:C₂₃H₁₅F₈N₃Os

Molecular Weight:533.44

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

BL-918 (compound 33i) is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. BL-918 exerts its cytoprotective autophagic effect by targeting ULK complex. BL-918 has the potential for Parkinson’s disease (PD) treatment.

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