Imetit dihydrobromide;VUF 8325 dihydrobromide

CAS NO.:32385-58-3

Molecular Formula:C₆H₁₂Br₂N₄S

Molecular Weight:332.06

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Imetit dihydrobromide (VUF 8325 dihydrobromide) is a high affinity and potent agonist of histamine H3 and H4 receptors, with Ki values of 0.3 and 2.7 nM, respectively. Imetit mimics histamine effect in triggering a shape change in eosinophils (EC50=25 nM).

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