PNU-120596;NSC216666

CAS NO.:501925-31-1

Molecular Formula:C₁₃H₁₄ClN₃O₄

Molecular Weight:311.72

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

PNU-120596 (NSC 216666 ) is a potent and selective positive allosteric α7 nAChR modulator with an EC50 of 0.2 μM. IC50 value: 0.2 uM (EC50) . Target: α7 in vitro: PNU-120596 increases agonist (Ach)-evoked calcium flux mediated by an engineered variant of the human α7 nAChR.

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